Vitamin B12 Biosynthesis
نویسندگان
چکیده
منابع مشابه
Vitamin B12 and protein biosynthesis. VI. Relation of vitamin B12 to amino acid activation.
It has been reported (l-5) from this laboratory that vitamin Blz functions in vivo and in vitro in the incorporation of amino acids into protein. There was observed a reduction in the incorporation of amino acids into protein in vitamin Brz-deficient pigs and rats in vivo as compared to normal animals (4). Similar reduction in the incorporation of amino acids was observed upon incubation of liv...
متن کاملAnaerobic biosynthesis of the lower ligand of vitamin B12.
Vitamin B12 (cobalamin) is required by humans and other organisms for diverse metabolic processes, although only a subset of prokaryotes is capable of synthesizing B12 and other cobamide cofactors. The complete aerobic and anaerobic pathways for the de novo biosynthesis of B12 are known, with the exception of the steps leading to the anaerobic biosynthesis of the lower ligand, 5,6-dimethylbenzi...
متن کاملOral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency.
BACKGROUND Vitamin B12 deficiency is common, and the incidence increases with age. Most people with vitamin B12 deficiency are treated in primary care with intramuscular (IM) vitamin B12. Doctors may not be prescribing oral vitamin B12 formulations because they may be unaware of this option or have concerns regarding its effectiveness. OBJECTIVES To assess the effects of oral vitamin B12 vers...
متن کاملVitamin B12 Deficiency
Functional vitamin B12 deficiency is a syndrome where a wide variety of symptoms in the presence of “normal” serum levels of the vitamin respond to vitamin B12 therapy. A series of patients with functional vitamin B12 deficiency are described whose presenting features were drenching night sweats and fatigue. Reliance on serum vitamin B12 levels as a diagnostic test would have obscured the cause...
متن کاملVitamin B12 monograph
While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a n...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1968
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)93549-0